Random App Stack Connect or Error

Hello Everyone,

I'm having an odd problem with AV 2.11.  We are getting random behavior where some of the time the App Stacks connect to the desktop without a problem and other times a message stating that there was a problem communicating with the agent appears on the desktop and none of the App Stacks appear.

Addressed: firewall ports / open, vCenter role and permissions / admin level, all there / no match to any specific ESXi host; no established pattern of any kind.

Just wondering if anyone else out there has experienced this issue. 

- ESXi 6.0 U2

- Server 2012 R2

- AV 2.11

- Horizon View 7.0.1

Thanks in advance.